Next Generation Sequencing
Our comprehensive genomics services include nucleic acid isolation, qPCR, and whole exome sequencing, targeting diverse organisms and disease-specific genes. We offer whole genome sequencing for detailed insights into ancestry, health, and genetic traits, and transcriptome analysis to investigate gene expression changes. Additionally, our metagenomics services identify unknown species and their environmental interactions, while our epigenetics services analyze heritable chemical modifications affecting gene expression. Trust our expertise for advanced sequencing and precise genetic analysis.
Nucleic Acid Extraction
CellSeq offers specialized nucleic acid isolation services for Microarray and NGS applications, with expertise in extracting gRNA and gDNA from diverse organisms and tissue types.
Key Points
- Expertise in isolating nucleic acids from prokaryotes, viruses, lower eukaryotes, plants, animals, and metagenomes from various sources.
- Specialized services for extracting mitochondrial DNA, chloroplast DNA, and serum nucleic acids.
- Quality checks on nucleic acids using Bioanalyzer, Tape station, and Qubit fluorometer for integrity and purity.
qPCR/PCR
Quantitative PCR (qPCR) is a versatile technique for precise RNA/DNA quantification using SYBR or TaqMan methods, ensuring efficient, reliable results without post-PCR manipulation.
Key Points
- Utilizes SYBR and TaqMan for sensitive, precise RNA/DNA quantification.
- Eliminates need for post-PCR sample manipulation, streamlining processes.
- Nucleic acid integrity checked with Bioanalyzer, Tape station, Qubit fluorometer.
Whole Exome Sequencing
Whole exome sequencing captures and sequences exonic genome regions, uncovering genetic variations related to diseases or traits cost-effectively.
Key Points
- Identifies SNPs and indels through comparison with a reference genome.
- Variations annotated to evaluate gene function and disease correlation.
- Includes mitochondrial genes in the comprehensive exome panel for insights.
Metagenome Sequencing
Metagenomics studies species' taxonomic and physiological traits from their natural habitats, aiding in species identification and understanding their environmental interactions.
Key Points
- Identifies unknown species and their interactions with the environment.
- Uses computational techniques to handle diverse samples and datasets.
- Extracts valuable biological data to advance scientific knowledge.
Epigenetics
Epigenetic changes alter gene expression without changing the DNA sequence, including chemical modifications to DNA and proteins. We offer comprehensive sequencing and analysis of epigenomic datasets.
Key Points
- Analyzes histone modifications and DNA methylation level variations.
- Examines heritable chemical alterations impacting gene expression.
- Provides thorough sequencing and analysis services for epigenomic data.
Transcriptome Sequencing
The transcriptome encompasses all RNA transcripts in a specific cell type. Our services analyze transcriptome changes to determine gene expression under various conditions.
Key Points
- Specialists in transcriptome dataset analysis for gene expression.
- Offers total RNA, mRNA, small RNA, miRNA, and custom RNA sequencing.
- Investigates changes in transcriptome to understand organism's response.
Targeted Exome Sequencing
Our disease-specific exome panels focus on genes linked to specific diseases, enhancing detection sensitivity and cost-effectiveness through targeted sequencing.
Key Points
- Curated panels target genes associated with specific diseases.
- Enhances detection sensitivity and optimizes sequencing costs.
- Offers customized targeted sequencing for detailed genetic information.
Whole Genome Sequencing
Our Whole Genome Sequencing service uses advanced technology to explore your genetic makeup, revealing insights into ancestry, health predispositions, and genetic traits.
Key Points
- Identifies key variations like SNPs and structural variants.
- Provides insights into ancestry, health, and genetic traits.
- Expert analysis empowers informed health and future decisions.